I just made my new pedalboard, and there are 13 pedals on it.
So, as you could expect, there is some signal loss, and so I decided to buy myself one of these tone buffers.
As I said already, there is some signal loss, but not a huge one when just going through the pedals, but enough to make some audible difference. When I put the buffer in front of my pedal chain, there was some improvement, but I'm not impressed that much. I watched some reviews on u-tube, and there was huge difference between going through the pedals, or longer cables, and going through the buffer in the front.
I recorded some audio clips with my SURE SM58 in front of the amp, and I played both my Fender strat, and Gibson LP, clean, and overdrive channel, in every combination (staight in the amp, throgh pedals, through the buffer) so I'm sure about what I said before. It's an improvement, but is it worth the money???
Since I bought it, I'm going to keep it, but I'm not sure if I'd do it again. Maybe there would be bigger improvement if there was bigger signal loss to start with.